I’ve been running stuff the last few weeks.
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It’s time for a points update but the internet may be down until Monday 
BIG NEWS!!!
World Community Grid is officially restarting BOINC
Dear 1695814,
We are proud to announce that after months of preparation and testing, the World Community Grid is ready to fully restart operations as one of the most cost efficient and powerful supercomputers in the world, dedicated exclusively to crunching data for scientific research that benefits the world.
After a long process of rebuilding WCG at Krembil Research Institute in Toronto, Canada, the platform is stable for broader use. Existing projects have prepared new workunits, and we have started to work on onboarding new projects.
We are reaching out to ask you to join the WCG community once again, and help transform open science through global collaboration, citizen engagement and youth outreach. As a World Community Grid volunteer your devices perform research calculations when idle or with what they can spare without impeding your personal use of them.
WCG is a safe, secure, and easy way to contribute to science. WCG has been built using the principle of security by design. Your personal information will never be shared, ever. The software cannot access your personal files, and security experts constantly test the system for any vulnerabilities or vectors of attack.
With your help, scientists can identify the most important results to study in the lab, accelerating discoveries that save lives and address global challenges.
Since 2004, more than 7.5M computers and Android devices have contributed to the network that makes up WCG, and over 2.4M years of computing power has been contributed to date. WCG condenses computational time to allow scientists to answer the world’s most pressing questions more quickly, more thouroughly, and cost efficiently by directing their limited budgets away from the generation and towards the analysis and interpretation of results.
Help us make a difference and support science at the World Community Grid! With support from volunteers from around the world, partners, and funders, people contribute to scientific discoveries.
Please re-join us in the WCG Community and help to accelerate science by creating a supercomputer empowered by a global community of volunteers:
[
Join World Community Grid →
](World Community Grid)Your individual contribution may seem small but together we are making the impossible possible, and democratizing access to incredibly expensive supercomputers with your help.
Thanks for your support,
WCG Team at Krembil Research Institute, UHN
Just in case you need the team info, here it is from the OP:
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Here’s the monthly update on World Community Grid points:
Statistics last updated: 10/3/22 23:59:59 (UTC) [4 hour(s) ago]
Member Name Points Monthly
Generated Change
mbplatt 169,530,627 1,163,593
KlaymenAO 155,076,927 398,939
1695814 75,265,959
Wannabe Actuary 59,021,321 536,456
Macroman 57,965,446 32,915
Actuarialsuck 30,162,993 187,084
yoyo_58 27,868,143 156,062
Breadmaker 9,806,079 9,472
meepbobeep 9,320,074 29,621
SpaceLobster 3,752,682 85,205
EffNine 1,750,671
celalta 695,450
GoA_Kenny 178,190 719
Available WCG Projects
OpenPandemics - COVID-19
Africa Rainfall Project
Help Stop TB
Mapping Cancer Markers
Smash Childhood Cancer
WCG discussion forums can be found here .
Here’s the monthly update on Folding@Home points:
Monthly
Name Credit Change
1695814 26,324,991 1,317,580
Rick_G 10,012,219 4,600
Celalta 9,192,677 1,613,036
GoA_Kenny 3,641,538 149,285
Breadmaker 3,566,834 98,536
Typical Folding@Home Projects
COVID-19
Alzheimer’s
Cancer
Huntington’s
Parkinson’s
For a comprehensive list see https://apps.foldingathome.org/psummary
If you’d like to join us in finding a cure for COVID-19, Cancer, Ebola, AIDS, and other stuff, see the OP ( <-- clicky clicky! ) for links to get the downloads
That’s weird. I thought WCG was running. It certainly shows up as the screen saver on at least one computer. I’ll have to look into that, at some point.
ARP unit 37% after 15.5 hours. So s…l…o…w… 
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I tawt I taw a putty tat…
…or maybe a work unit.
From the FaceOff:
text
Research update from the SCC team (October 2022)
Smash Childhood Cancer (SCC) team provided an exciting update on the validation results for the three projects.
Project: Smash Childhood Cancer
Published on: 28 Oct 2022
As scientific discoveries on the WCG platform take considerable time to be analyzed and validated, it is with great enthusiasm we share with you a recent update from Smash Childhood Cancer team.
Making Chemotherapy Work Better: PAX-FOXO1 inhibitors for childhood muscle cancer
In work supported by the Megan’s Mission Foundation, the Children’s Cancer Therapy Development Institute (cc-TDI.org; under leadership of Dr. C. Keller) has collaborated with Dr. Tyuji Hoshino at Chiba University and the World Community Grid (WCG) to develop the unlikely drug: an inhibitor of a ‘transcription factor’. In the childhood muscle cancer rhabdomyosarcoma, the two normal transcription factors PAX3 and FOXO1 ‘break’ and then fuse to one another. The resulting PAX-FOXO1 transcription factor drives a program of other genes to go on that lead to chemotherapy resistance, relapse and sometimes demise. Through the WCG, 8 million compounds were screened and a mere 24 compounds were identified. Thus far, 5 have been validated to stop the action of the PAX-FOXO1 transcription factor. The cc-TDI project lead is Kiyo Nagamori.
Stopping Metastasis of Childhood Sarcomas
In work supported by the Pheonix Spangler Foundation, the Children’s Cancer Therapy Development Institute (cc-TDI.org) has collaborated with Dr. Tyuji Hoshino at Chiba University and the World Community Grid (WCG) to develop a small molecule inhibitor of the Osteopontin protein. Osteopontin is a protein made by cancer cells as a way to invite blood vessels to grow nearer. These vessels are then a pathway to spread throughout the body. In work evaluating computationally-modeling chemicals and experimentally identified compounds from collaborator Aykut Uren at Georgetown University, we have identified compounds that bind Osteopontin. The next step is to determine if these compounds stop the blood vessel formation and metastasis that occur as a result of Osteopontin. Genetically-engineered mice with normal levels or absence of Osteopontin make this work possible. The cc-TDI project lead is Shefali Chauhan.
Stopping the Driver of TrkB Neuroblastoma
In studies honoring Alyssa, the Children’s Cancer Therapy Development Institute (cc-TDI.org) has collaborated with Dr. Tyuji Hoshino and Dr. Akira Nakagawara at Chiba University and the World Community Grid (WCG) to develop next-generation, selective inhibitor of the TrkB protein. TrkB drives the growth and progression of childhood nerve cell cancer, neuroblastoma. TrkB is the sister protein to TrkA, which has become of great pharmaceutical interest in sarcomas and lung cancers. The TrkB inhibitors developed by evolving chemicals derived from computational modeling have increased solubility but retain activity against TrkB. The cc-TDI project lead is Xiaolei Lian.
Thank you Dr. Keller and the rest of the SCC team for your incredible work. We look forward to hearing about further success of these treatments, and to run new predictions on the WCG for the new targets.
WCG team at Krembil Research Institute
tl;dr: Childhood Cancers are being Smashed!!! …(…little by little)
Childhood cancer can go FLUFF itself!!! 
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The childhood cancer project has not run for about 2 years!
Here’s the monthly update on World Community Grid points:
Statistics last updated: Statistics last updated: 10/30/22 23:59:59 (UTC) [25 hour(s) ago]
Member Name Points Monthly
Generated Change
mbplatt 175,390,437 5,859,810
KlaymenAO 157,018,421 1,941,494
1695814 76,133,376 867,417
Wannabe Actuary 60,171,597 1,150,276
Macroman 58,213,229 247,783
Actuarialsuck 31,730,840 1,567,847
yoyo_58 28,167,236 299,093
Breadmaker 9,904,691 98,612
meepbobeep 9,441,518 121,444
SpaceLobster 4,260,116 507,434
EffNine 1,750,671
celalta 695,450
GoA_Kenny 223,915 45,725
Available WCG Projects
OpenPandemics - COVID-19
Africa Rainfall Project
Help Stop TB
Mapping Cancer Markers
Smash Childhood Cancer
WCG discussion forums can be found here .
Here’s the monthly update on Folding@Home points:
Monthly
Name Credit Change
1695814 26,593,150 268,159
Rick_G 10,335,812 323,593
Celalta 10,014,044 821,367
GoA_Kenny 3,948,680 307,142
Breadmaker 3,667,837 101,003
Typical Folding@Home Projects
COVID-19
Alzheimer’s
Cancer
Huntington’s
Parkinson’s
For a comprehensive list see https://apps.foldingathome.org/psummary
If you’d like to join us in finding a cure for COVID-19, Cancer, Ebola, AIDS, and other stuff, see the OP ( <-- clicky clicky! ) for links to get the downloads
ARP unit is at 10% after 4 1/2 hours. I cranked the CPU to 90%; I might consider 95 depending how far it gets in the next day or so.
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Here’s the monthly update on World Community Grid points:
Statistics last updated: 12/1/22 23:59:59 (UTC) [2 hour(s) ago]
Member Name Points Monthly
Generated Change
mbplatt 182,993,511 7,603,074
KlaymenAO 158,831,840 1,813,419
1695814 77,024,024 890,648
Wannabe Actuary 62,228,842 2,057,245
Macroman 58,468,860 255,631
Actuarialsuck 33,342,364 1,611,524
yoyo_58 29,089,364 922,128
Breadmaker 10,083,805 179,114
meepbobeep 9,595,683 154,165
SpaceLobster 4,901,653 641,537
GoA_Kenny 293,465 69,550
Available WCG Projects
OpenPandemics - COVID-19
Africa Rainfall Project
Help Stop TB
Mapping Cancer Markers
Smash Childhood Cancer
WCG discussion forums can be found here .
Here’s the monthly update on Folding@Home points:
Monthly
Name Credit Change
1695814 27,004,670 411,520
Celalta 11,662,557 1,326,745
GoA_Kenny 4,036,814 88,134
Breadmaker 3,807,266 139,429
Typical Folding@Home Projects
COVID-19
Alzheimer’s
Cancer
Huntington’s
Parkinson’s
For a comprehensive list see https://apps.foldingathome.org/psummary
If you’d like to join us in finding a cure for COVID-19, Cancer, Ebola, AIDS, and other stuff, see the OP ( <-- clicky clicky! ) for links to get the downloads
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Got an ARP unit at 53.77% after 1 day, 2 1/2 hours. CPU is at 90%!!!
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I also have an ARP on my work laptop: 19% after 7 hours. Crankin’ the CPU to 90%!!!
Gonna take some time to do the things we never had (ooh, ooh) 
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Here’s the monthly update on World Community Grid points:
Statistics last updated: 12/31/22 23:59:59 (UTC) [2 hour(s) ago]
Member Name Points Monthly
Generated Change
mbplatt 187,474,715 4,481,204
KlaymenAO 161,188,547 2,356,707
1695814 77,841,995 817,971
Wannabe Actuary 62,446,022 217,180
Macroman 58,717,093 248,233
Actuarialsuck 33,580,233 237,869
yoyo_58 29,961,872 872,508
Breadmaker 10,226,979 143,174
meepbobeep 9,717,601 121,918
SpaceLobster 5,482,703 581,050
GoA_Kenny 318,233 24,768
Available WCG Projects
OpenPandemics - COVID-19
Africa Rainfall Project
Help Stop TB
Mapping Cancer Markers
Smash Childhood Cancer
WCG discussion forums can be found here .
Here’s the monthly update on Folding@Home points:
Monthly
Name Credit Change
1695814 27,004,670
Celalta 12,199,415 536,858
GoA_Kenny 4,251,977 215,163
Breadmaker 3,960,164 152,898
Typical Folding@Home Projects
COVID-19
Alzheimer’s
Cancer
Huntington’s
Parkinson’s
For a comprehensive list see https://apps.foldingathome.org/psummary
If you’d like to join us in finding a cure for COVID-19, Cancer, Ebola, AIDS, and other stuff, see the OP ( <-- clicky clicky! ) for links to get the downloads
I’m almost out of work units on my work and personal laptops. 
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