Help find a cure for COVID-19, Cancer, Ebola, AIDS, and other stuff

Stoopd rai-SINS!!! :-1: :unamused: :nauseated_face:

And I have no idea what happened with Folding@Home. :man_shrugging:

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This almost sounds made up:

The WCG website is currently down because the database server became unavailable on the network and rebooting it threw a libvirt error in our cloud environment. As a result, we are currently unable to recover the server until we hear back from hosting.

For the kids out there…

The Computation Moonshot, a competition encouraging high school students to learn about data science and distributed computing, began today. Read more here:

Let’s stuff the ballot box like a thanksgiving turkey…

BOINC is a finalist for a United Nations-sponsored award.

We urgently need your help by March 31st 2024.

As you know, BOINC enables anyone with a computer to contribute to cutting-edge research. The World Community Grid is one of about 30 active science projects that uses BOINC to accelerate critical scientific research.

The World Summit on the Information Society (WSIS) is a United Nations-sponsored initiative aimed at harnessing the potential of information and communication technologies to build inclusive and equitable information societies worldwide. BOINC has been nominated for a prize at the 2024 forum, and has passed initial hurdles. The final step requires public votes. The award would be a very nice boost and validation for BOINC. Voting is simple and takes just a few minutes; instructions are here: https://docs.google.com/…/1x9Xi3tq7Y9dlDD0Xb0Ul0yY…/edit

The deadline for votes is Sunday: 31 March 2024, 23:00 UTC+02:00

I clicked on the link so you don’t have to:

messy instructions

Voting Process

WSIS PRIZES 2024

The World Summit on the Information Society (WSIS) is a United Nations-sponsored initiative aimed at harnessing the potential of information and communication technologies to build inclusive and equitable information societies worldwide. BOINC has been nominated for a prize at the 2024 forum, and has passed initial hurdles; the next and last step (“Phase 3”) requires public votes. – Volunteer voting for volunteer computing :slight_smile:

Instructional Video

Steps to Vote

Go to WSIS Prizes 2024https://www.itu.int/net4/wsis/stocktaking/Prizes/2024 – and click “Vot

Go to e”

  1. …this will scroll the page down to the “Phase 3: Voting Phase” section; click “Vote” again here.

  2. On the resulting login page, click “Register as a New User”

  3. Go to the email you used in registration; look for an email with the subject line “Confirm your WSIS account” (from WSIS-confirmation@bb.itu.int). → Click the button in that email to “Confirm Registration”

  4. On the resulting webpage, click to return to the login form

  5. On the login form, login

  6. On the page shown after login, click “Voting Form”

  7. In the voting form,

  8. at top of the form, there is a grey box which is a dropdown menu; click and select category “AL C7. E-Science”. (*Note: you may need to scroll the list to see this option. Also note: there are several “AL C7” topics; we are in “AL C7 E-Science”)

  9. After selecting the category, scroll down to find “Berkeley Open Infrastructure for Network Computing”

  10. Click “Vote for this Project” (N.b. there doesn’t seem to be any confirmation; you are just returned to the form to browse/select projects in other categories and category “AL C7. E-Science” is no longer available in the dropdown menu). But you can see your votes here: Log in | WSIS Stocktaking Platform

Here’s the short version:
click → WSIS Prizes 2024
click [ vote → ]
click [ vote → ] again
oferpetesake [register as a new user], go through all of those steps
click [ voting form → ]
In the gray drop down select “AL C7 E-Science”
Then do a find on “Berkeley Open Infrastructure for Network Computing” (for me it was way at the bottom)
Finally, [Vote For This Project]
Then, I think it takes you to another category where you can vote for something else if you wish.
Sheesh, that’s a lot of work.

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Here’s the monthly update on World Community Grid points:

Member Name           Points    Monthly
                   Generated     Change
mbplatt          226,525,382  2,046,680
KlaymenAO        201,776,714    873,703
1695814           93,945,629    181,319
Wannabe Actuary   73,790,800    699,384
Macroman          62,585,798    149,891
SpaceLobster      13,963,205    170,214
Breadmaker        11,950,824    120,349
meepbobeep        11,577,074    159,400
GoA_Kenny          1,276,453    110,509

Statistics last updated: 3/31/24 23:59:59 (UTC) [0 hour(s) ago]

Available WCG Projects:
OpenPandemics - COVID-19
Africa Rainfall Project
Help Stop TB
Mapping Cancer Markers
Smash Childhood Cancer

WCG discussion forums can be found here .

Here’s the monthly update on Folding@Home points:

                          Monthly
Name            Credit     Change
1695814     35,387,435  1,123,922
GoA_Kenny    7,047,078    302,435
yoyo         8,326,357    856,074
Breadmaker   4,998,069      3,400

Welcome, back to the fold, @Breadmaker!

Typical Folding@Home Projects

COVID-19
Alzheimer’s
Cancer
Huntington’s
Parkinson’s
For a comprehensive list see https://apps.foldingathome.org/psummary

If you’d like to join us in finding a cure for COVID-19, Cancer, Ebola, AIDS, and other stuff, see the OP ( <-- clicky clicky! ) for links to get the downloads

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I go foldie foldie!!! :open_file_folder:

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Whyyyy would I spend all that time voting for something that is down all the time?

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Because if you vote for it then they’ll have the resources to be able to keep it up more often. :judge:

From the face off, https://www.worldcommunitygrid.org/about_us/article.s?articleId=811

text with links

ARP restart update

The ARP team is preparing to restart after the project was put on pause in December 2022. This article outlines the steps that we are taking in order to restart this project.


Project: Africa Rainfall Project

Published on: 25 Apr 2024


Background

The Africa Rainfall Project (ARP) aims to simulate rainstorms in sub-Saharan Africa to improve regional weather forecasts. The goal is to run a weather simulation at a high resolution (1 km) for the whole region for a period of one year. Providing accurate weather predictions is crucial for self-sufficiency of the local farming community. By comparing results obtained through computing rainfall data from various sources using the World Community Grid, scientists can create increasingly more accurate forecasts, improve future simulations and in turn weather predictions. To read more about this project, see our March 2022 research update.

In December 2022, the project was put on pause due to capacity limitations of their storage system. To read more about the details of this storage limitation, please refer to ARP update from March 2023. As we shared in a July 2023 update, part of this challenge was that the ARP team’s storage support from SURF, the cooperative association of Dutch educational and research institutions, came to an end. Fortunately, Amazon Web Services (AWS) agreed to host the data, and thus began the process of moving the data. Since the move is complete, the ARP team has been taking steps to make the data more broadly accessible through the AWS platform, but this work is still in the early stages. Currently, the focus is on finalizing the preparation of new work units and generating the data needed to restart ARP.

ARP Restart Update

We have started to work on resuming sending out ARP1 work units to volunteers. Our research partners at TU Delft have already sent us most of the required scripts and documentation, which we have reviewed and implemented locally. Currently, we are awaiting a determination on whether we will receive the rest of the required data and application code directly, or whether we will need to reproduce these components from documentation provided by the TU Delft team. We have assessed that both approaches are feasible, and wanted to let volunteers know that we are on a defined path to restarting ARP1 in the coming weeks.

The timeline of a possible restart of this project depends on the information from the ARP team. If the code and data required is not fully available to us, we will need to build out the missing components of the pipeline for generating new ARP1 work and confirm that we are able to reproduce the same inputs as we previously received from TU Delft servers to validate the new pipeline. Regardless, there will be no change and no action required by volunteers to facilitate the process and when ARP1 restarts work unit distribution will be the same as before.

Figure 1. An example of a unit. Each unit comprises three nested domains (1-way) with respectively 9 km, 3 km, and 1 km resolution.

Thanks to the ARP team for their continued partnership with the WCG. If you have any questions or comments, please leave them in this thread for us to answer.

chatgptsummary

The Africa Rainfall Project (ARP) is gearing up to resume its operations after a pause since December 2022 due to storage limitations. The project aims to simulate rainstorms in sub-Saharan Africa to enhance regional weather forecasts. The team has overcome storage challenges by transitioning to Amazon Web Services (AWS) to host data. Now, they are finalizing preparations to restart ARP1 work units. They’ve received most scripts and documentation from research partners at TU Delft, with the remaining data and application code pending. The timeline for restarting ARP1 depends on acquiring these components. Regardless, volunteers need not take any action, and when ARP1 resumes, work unit distribution will remain unchanged. The ARP team appreciates the ongoing partnership with the World Community Grid (WCG) and invites questions or comments from volunteers.

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Here’s the monthly update on World Community Grid points:

Member Name           Points    Monthly
                   Generated     Change
mbplatt          236,064,555  9,539,173
KlaymenAO        205,453,781  3,677,067
1695814           94,123,668    178,039
Wannabe Actuary   75,232,583  1,441,783
Macroman          62,835,201    249,403
SpaceLobster      14,653,448    690,243
Breadmaker        12,173,213    222,389
meepbobeep        11,765,211    188,137
GoA_Kenny          1,387,144    110,691

Statistics last updated: 4/29/24 23:59:59 (UTC) [24 hour(s) ago] (ooh, I just made it in time, as, right now, “The page you requested is currently unavailable because the statistics are being updated. The statistics update will finish in about 21 minutes .” yee haw!)

Available WCG Projects:
OpenPandemics - COVID-19
Africa Rainfall Project
Mapping Cancer Markers
Smash Childhood Cancer
Help Stop TB

WCG discussion forums can be found here .

Here’s the monthly update on Folding@Home points:

                          Monthly
Name            Credit     Change
1695814     36,404,342  1,016,907
GoA_Kenny    7,468,141    421,063
yoyo         8,326,357           
Breadmaker   5,022,609     24,540

@yoyo seems to be up and down on this one.

Typical Folding@Home Projects

COVID-19
Alzheimer’s
Cancer
Huntington’s
Parkinson’s
For a comprehensive list see https://apps.foldingathome.org/psummary

If you’d like to join us in finding a cure for COVID-19, Cancer, Ebola, AIDS, and other stuff, see the OP ( <-- clicky clicky! ) for links to get the downloads

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Via FleaceBook:

The MCM team continues to characterise lung cancer biomarkers identified in the MCM1 project. This update focuses on KLF5, a well-studied gene that has been implicated in several cancer types. KLF5 is a transcription factor, which is expressed across numerous organs and tissues. Read more here:

summary via chatgpt:

The MCM team’s latest update focuses on KLF5, a gene involved in various biological processes and linked to multiple cancer types, including lung cancer. KLF5 acts as a transcription factor and has implications in conditions like COPD, diabetic nephropathy, and lupus nephritis. Studies suggest it plays a protective role in lung cancer, particularly among non-smokers. The research aims to understand its significance in cancer detection, prognosis, and treatment.

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